NLRP4 polyclonal antibody
产品名称： NLRP4 polyclonal antibody
英文名称： NLRP4 polyclonal antibody
产品编号： PAB0268
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of NLRP4.
- Immunogen:
- A synthetic peptide corresponding to amino acids 139-157 of human NLRP4.
- Sequence:
- FAPKETGKQPRTVIIQGPQ
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Storage Buffer:
- In serum (0.05% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Application Image
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Immunohistochemistry (Frozen sections)
- Immunoprecipitation
- Entrez GeneID:
- 147945
- Gene Name:
- NLRP4
- Gene Alias:
- CLR19.5,FLJ32126,NALP4,PAN2,PYPAF4,RNH2
- Gene Description:
- NLR family, pyrin domain containing 4
- Omim ID:
- 609645
- Gene Ontology:
- Hyperlink
- Gene Summary:
- NALPs are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Most short NALPs, such as NALP4, have an N-terminal pyrin (MEFV; MIM 608107) domain (PYD), followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. The long NALP, NALP1 (MIM 606636), also has a C-terminal extension containing a function to find domain (FIIND) and a caspase recruitment domain (CARD). NALPs are implicated in the activation of proinflammatory caspases (e.g., CASP1; MIM 147678) via their involvement in multiprotein complexes called inflammasomes (Tschopp et al., 2003 [PubMed 12563287]).[supplied by OMIM
- Other Designations:
- NACHT, LRR and PYD containing protein 4,NACHT, leucine rich repeat and PYD containing 4,PAAD and NACHT-containing protein 2,PYRIN-containing APAF1-like protein 4,nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 4,
- Related Disease